Background
We are now at the end of the cholesterol biosynthesis pathway, and have seen how cholesterol is synthesized from acetyl-CoA in a series of steps catalyzed by many different enzymes.
Challenge
How would the level of cholesterol change if the enzyme HMGCR was inhibited or decreased?
The level of cholesterol would be increased
The level of cholesterol would be decreased
No change in the level of cholesterol
Explanation
That’s correct! And that is how some cholesterol-lowering drugs work, by inhibiting the HMGCR enzyme. See how that
works in the Statin Pathway.
Continue to the Pathway Building Blocks track to learn the basics of drawing a pathway.
Explanation
Are you sure? Review the pathway and choose another answer.
